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In the world of over-the-counter and prescription medications, Brufen 400 mg stands out as one of the most commonly used drugs for treating pain, fever, and inflammation. Whether you’re dealing with a throbbing headache, sore muscles, or chronic joint pain, this medication is a go-to solution for millions worldwide.
But what exactly is Brufen 400 used for? What makes it so effective? And is it safe for everyone?
This informative guide provides answers to all your queries regarding Brufen 400, including its principal medical uses, advantages, dosage, side effects, precautions, and frequently asked questions.
Brufen 400 is a branded drug whose active ingredient is Ibuprofen. Ibuprofen is a non-steroidal anti-inflammatory drug (NSAID) which has the potency of lowering pain, fever, and inflammation.
Produced by Abbott, Brufen 400 is a tablet that is usually prescribed for short-term treatment in adults and children aged 12 years or more.
Brufen 400 (Ibuprofen 400 mg) acts to block enzymes called COX-1 and COX-2 (cyclooxygenase enzymes). These enzymes cause prostaglandins to be produced—chemical substances in the body that produce pain, inflammation, and fever.
By blocking prostaglandin production, Brufen 400 helps to:
Relieve pain
Reduce inflammation
Lower fever
Let’s break down the major medical applications of Brufen 400, based on clinical evidence and common practice:
One of the most common uses of Brufen 400 is to alleviate mild to moderate pain caused by:
Headaches and migraines
Back pain and muscle pain
Toothaches and dental surgery
Joint pain
Post-operative pain
Injuries like sprains and strains
Its ability to provide quick and lasting relief makes it ideal for both acute and recurring pain episodes.
Brufen 400 is an effective fever reducer, often used to treat high body temperatures caused by:
Viral infections (e.g., cold, flu)
Bacterial infections
Post-vaccination fever
Fever in adults and adolescents
Its dual role as an antipyretic and anti-inflammatory makes it superior to some other fever medications in inflammatory illnesses.
Brufen 400 is widely used in managing inflammation in both acute and chronic conditions, including:
Rheumatoid arthritis
Osteoarthritis
Ankylosing spondylitis
Tendonitis and bursitis
Post-surgical inflammation
It improves mobility and reduces swelling in joints and tissues, allowing for better physical function.
Menstrual cramps are often caused by the release of prostaglandins during menstruation. Brufen 400 effectively reduces:
Uterine cramps
Lower abdominal pain
Lower back discomfort
For many women, it is a reliable and fast-acting option to manage monthly period pain.
Dentists often prescribe Brufen 400 for:
Wisdom tooth extraction
Root canal pain
Toothaches
Post-operative gum inflammation
Its painkilling and anti-inflammatory effects make it ideal for managing short-term dental pain.
Whether due to physical activity, sports injuries, or overuse, Brufen 400 is commonly used to treat:
Muscle aches
Tendon injuries
Soft tissue swelling
Joint stiffness
Brufen 400 mg tablet is sometimes used under medical supervision for:
Migraine prevention (short-term)
Post-vaccination pain relief
Mild ear infections
Always consult your doctor before using Brufen for conditions not listed on the label.
| Benefit | Description |
|---|---|
| Reduces Inflammation | Treats joint swelling and redness |
| Relieves Pain | Effective for a wide range of pain types |
| Lowers Fever | Helps regulate body temperature in fever |
| Enhances Mobility | Useful in chronic joint disorders |
| Fast-Acting | Starts working within 30–60 minutes |
| Cost-Effective | Affordable and widely available |
Recommended dose: 400 mg every 4–6 hours
Maximum dose: Do not exceed 2400 mg in 24 hours without medical advice
Take after meals with a full glass of water
Swallow the tablet whole (do not crush or chew)
Avoid alcohol while taking Brufen
Avoid Brufen 400 if you:
Have stomach ulcers or bleeding disorders
Are allergic to NSAIDs or aspirin
Have kidney, liver, or heart conditions
Are pregnant in the third trimester
Are taking blood thinners or steroids
Suffer from uncontrolled hypertension or asthma
Like all medicines, Brufen 400 can cause side effects. Most are mild, but some can be serious.
Upset stomach
Nausea
Heartburn
Dizziness
Headache
Blood in stool or vomit
Chest pain or breathlessness
Swelling of face, hands, or feet
Jaundice (yellowing skin or eyes)
Severe skin rash or allergic reaction
Stop use immediately and consult a doctor if you notice any of the above.
Brufen 400 may interact with several medications. Inform your healthcare provider if you are taking:
Aspirin or other NSAIDs
Warfarin or blood thinners
Lithium or methotrexate
Corticosteroids
ACE inhibitors or diuretics
Pregnancy: Not recommended, especially during the third trimester
Breastfeeding: Generally safe in short-term, low-dose use. Consult your doctor
| Drug | Anti-inflammatory? | Pain Relief | Fever Control | GI Risk |
|---|---|---|---|---|
| Brufen (Ibuprofen) | Yes | Strong | Yes | Moderate |
| Paracetamol | No | Moderate | Yes | Low |
| Aspirin | Yes | Strong | Yes | High |
Brufen offers the best combination of pain relief and inflammation control, especially for joint and muscle-related issues.
Don’t exceed the recommended dose
Always take with food
Avoid alcohol
Don’t combine with other NSAIDs
Read the label or consult a pharmacist before use
You can take it occasionally for short-term relief. Long-term use should be under medical supervision due to potential kidney and stomach risks.
Brufen usually starts working in 30 to 60 minutes, with effects lasting around 4 to 6 hours.
Yes. Brufen has anti-inflammatory effects, which Paracetamol lacks, making it more effective for swelling and joint pain.
It’s best taken with or after food to minimize the risk of stomach upset.
Generally, yes. But if you experience drowsiness or dizziness, avoid driving or operating machinery.
Brufen 400 mg is a powerful and versatile tablet taken across the globe to treat pain, fever, and inflammation. From period cramps to arthritis attacks, it delivers quick relief and returns ease to everyday life.
Nonetheless, it must be used responsibly and in accordance with directions. Abuses or excesses may lead to dangerous side effects, particularly affecting the stomach, kidneys, and heart.
You should always consult your physician prior to taking or continuing Brufen 400, especially if you have underlying health conditions or are on other medications.